Effects of 3-octen-2-one on human olfactory receptor responses to vanilla flavor
Humans perceive most odors as complex mixtures influenced by interactions between odorant molecules. This study investigated how 3-octen-2-one, known to modulate vanilla aroma, affects human olfactory receptors using a sensor with all 388 receptor types. The results showed that vanilla flavor with 3-octen-2-one enhanced the response of the OR1D2 receptor compared with vanilla aroma and completely suppressed the response of the OR5K1 receptor.
The research findings have been published in the Bioscience, Biotechnology, and Biochemistry (2022, vol. 86, issue 11, p. 1562-1569) [1].